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N-Acetyl-cysteine causes analgesia by reinforcing the endogenous activation of type-2 metabotropic glutamate receptors

BACKGROUND: Pharmacological activation of type-2 metabotropic glutamate receptors (mGlu2 receptors) causes analgesia in experimental models of inflammatory and neuropathic pain. Presynaptic mGlu2 receptors are activated by the glutamate released from astrocytes by means of the cystine/glutamate anti...

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Detalles Bibliográficos
Autores principales:	Bernabucci, Matteo, Notartomaso, Serena, Zappulla, Cristina, Fazio, Francesco, Cannella, Milena, Motolese, Marta, Battaglia, Giuseppe, Bruno, Valeria, Gradini, Roberto, Nicoletti, Ferdinando
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543227/ https://www.ncbi.nlm.nih.gov/pubmed/23088864 http://dx.doi.org/10.1186/1744-8069-8-77

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