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Mechanistic studies of Gemcitabine-loaded nanoplatforms in resistant pancreatic cancer cells
BACKGROUND: Pancreatic cancer remains the deadliest of all cancers, with a mortality rate of 91%. Gemcitabine is considered the gold chemotherapeutic standard, but only marginally improves life-span due to its chemical instability and low cell penetrance. A new paradigm to improve Gemcitabine’s ther...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543259/ https://www.ncbi.nlm.nih.gov/pubmed/22998550 http://dx.doi.org/10.1186/1471-2407-12-419 |