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Bax/Mcl-1 balance affects neutrophil survival in intermittent hypoxia and obstructive sleep apnea: effects of p38MAPK and ERK1/2 signaling

BACKGROUND: Prolonged neutrophil survival is evident in various cardiovascular and respiratory morbidities, in hypoxic conditions in-vitro and in patients with obstructive sleep apnea (OSA) characterized by nightly intermittent hypoxia (IH). This may lead to persistent inflammation, tissue injury an...

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Detalles Bibliográficos
Autores principales:	Dyugovskaya, Larissa, Polyakov, Andrey, Cohen-Kaplan, Victoria, Lavie, Peretz, Lavie, Lena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543281/ https://www.ncbi.nlm.nih.gov/pubmed/23088735 http://dx.doi.org/10.1186/1479-5876-10-211

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