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Fenretinide Causes Emphysema, Which Is Prevented by Sphingosine 1-Phoshate
Sphingolipids play a role in the development of emphysema and ceramide levels are increased in experimental models of emphysema; however, the mechanisms of ceramide-related pulmonary emphysema are not fully understood. Here we examine mechanisms of ceramide-induced pulmonary emphysema. Male Sprague-...
Autores principales: | Yasuo, Masanori, Mizuno, Shiro, Allegood, Jeremy, Kraskauskas, Donatas, Bogaard, Harm J., Spiegel, Sarah, Voelkel, Norbert F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543313/ https://www.ncbi.nlm.nih.gov/pubmed/23326540 http://dx.doi.org/10.1371/journal.pone.0053927 |
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