Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in Acute lung injury to Reduce Pulmonary dysfunction (HARP-2) trial: study protocol for a randomized controlled trial

BACKGROUND: Acute lung injury (ALI) is a common devastating clinical syndrome characterized by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure. There are in vitro, animal studies and pre-clinical data suggesting that statins may be beneficial in ALI....

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Detalles Bibliográficos
Autores principales: McAuley, Daniel F, Laffey, John G, O’Kane, Cecilia M, Cross, Mark, Perkins, Gavin D, Murphy, Lynn, McNally, Christine, Crealey, Grainne, Stevenson, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543316/
https://www.ncbi.nlm.nih.gov/pubmed/22985805
http://dx.doi.org/10.1186/1745-6215-13-170

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