Targeting CD44-STAT3 Signaling by Gemini Vitamin D Analog Leads to Inhibition of Invasion in Basal-Like Breast Cancer

BACKGROUND: CD44, a transmembrane glycoprotein, is a major receptor for extracellular proteins involved in invasion and metastasis of human cancers. We have previously demonstrated that the novel Gemini vitamin D analog BXL0124 [1α,25-dihydroxy-20R-21(3-hydroxy-3-deuteromethyl-4,4,4-trideuterobutyl)...

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Detalles Bibliográficos
Autores principales: So, Jae Young, Smolarek, Amanda K., Salerno, David M., Maehr, Hubert, Uskokovic, Milan, Liu, Fang, Suh, Nanjoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543376/
https://www.ncbi.nlm.nih.gov/pubmed/23326564
http://dx.doi.org/10.1371/journal.pone.0054020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543376/
https://www.ncbi.nlm.nih.gov/pubmed/23326564
http://dx.doi.org/10.1371/journal.pone.0054020

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