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Structure Prediction and Validation of the ERK8 Kinase Domain

Extracellular signal-regulated kinase 8 (ERK8) has been already implicated in cell transformation and in the protection of genomic integrity and, therefore, proposed as a novel potential therapeutic target for cancer. In the absence of a crystal structure, we developed a three-dimensional model for...

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Detalles Bibliográficos
Autores principales:	Strambi, Angela, Mori, Mattia, Rossi, Matteo, Colecchia, David, Manetti, Fabrizio, Carlomagno, Francesca, Botta, Maurizio, Chiariello, Mario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543423/ https://www.ncbi.nlm.nih.gov/pubmed/23326322 http://dx.doi.org/10.1371/journal.pone.0052011

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