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Engineered Drug Resistant γδ T Cells Kill Glioblastoma Cell Lines during a Chemotherapy Challenge: A Strategy for Combining Chemo- and Immunotherapy
Classical approaches to immunotherapy that show promise in some malignancies have generally been disappointing when applied to high-grade brain tumors such as glioblastoma multiforme (GBM). We recently showed that ex vivo expanded/activated γδ T cells recognize NKG2D ligands expressed on malignant g...
Autores principales: | Lamb, Lawrence S., Bowersock, Joscelyn, Dasgupta, Anindya, Gillespie, G. Yancey, Su, Yun, Johnson, Austin, Spencer, H. Trent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543433/ https://www.ncbi.nlm.nih.gov/pubmed/23326319 http://dx.doi.org/10.1371/journal.pone.0051805 |
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