In vivo knockdown of intersectin-1s alters endothelial cell phenotype and causes microvascular remodeling in the mouse lungs

Intersectin-1s (ITSN-1s) is a general endocytic protein involved in regulating lung vascular permeability and endothelial cells (ECs) survival, via MEK/Erk1/2(MAPK) signaling. To investigate the in vivo effects of ITSN-1s deficiency and the resulting ECs apoptosis on pulmonary vasculature and lung h...

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Detalles Bibliográficos
Autores principales: Bardita, Cristina, Predescu, Dan, Justice, Matthew J., Petrache, Irina, Predescu, Sanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543613/
https://www.ncbi.nlm.nih.gov/pubmed/23054079
http://dx.doi.org/10.1007/s10495-012-0762-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543613/
https://www.ncbi.nlm.nih.gov/pubmed/23054079
http://dx.doi.org/10.1007/s10495-012-0762-x

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