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Sorafenib Inhibits Tumor Growth and Improves Survival in a Transgenic Mouse Model of Pancreatic Islet Cell Tumors

Background. The purpose of the study was to evaluate Sorafenib (BAY 43-9006) derived receptor tyrosine kinase inhibition on tumor progression in murine islet cell tumors. Sorafenib is considered to be a potent inhibitor of tumor angiogenesis and neovascularization in various solid tumors. Rip1Tag2 m...

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Detalles Bibliográficos
Autores principales:	Fendrich, Volker, Maschuw, Katja, Rehm, Johannes, Buchholz, Malte, Holler, Julia P., Slater, Emily P., Bartsch, Detlef K., Waldmann, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Scientific World Journal 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543792/ https://www.ncbi.nlm.nih.gov/pubmed/23346016 http://dx.doi.org/10.1100/2012/529151

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