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Decreased Metabolism in the Cerebral Cortex in Early-Stage Huntington's Disease: A Possible Biomarker of Disease Progression?

BACKGROUND AND PURPOSE: Huntington's disease (HD) is an autosomal-dominant inherited neurodegenerative disorder. Genetic analysis of abnormal CAG expansion in the IT15 gene allows disease confirmation even in the preclinical stage. However, because there is no treatment to cure or delay the pro...

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Detalles Bibliográficos
Autores principales: Shin, Hyeeun, Kim, Man Ho, Lee, Su Jin, Lee, Kyung-Han, Kim, Mi-Jung, Kim, Ji Sun, Cho, Jin Whan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neurological Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543905/
https://www.ncbi.nlm.nih.gov/pubmed/23346156
http://dx.doi.org/10.3988/jcn.2013.9.1.21