Cargando…

Understanding Disease Susceptibility through Population Genomics

Genetic epidemiology studies have established that the natural variation of gene expression profiles is heritable and has genetic bases. A number of proximal and remote DNA variations, known as expression quantitative trait loci (eQTLs), that are associated with the expression phenotypes have been i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Seonggyun, Lee, Junnam, Kim, Sangsoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korea Genome Organization 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543923/ https://www.ncbi.nlm.nih.gov/pubmed/23346035 http://dx.doi.org/10.5808/GI.2012.10.4.234

Ejemplares similares

Short Reads Phasing to Construct Haplotypes in Genomic Regions That Are Associated with Body Mass Index in Korean Individuals
por: Lee, Kichan, et al.
Publicado: (2014)

The Construction of Regulatory Network for Insulin-Mediated Genes by Integrating Methods Based on Transcription Factor Binding Motifs and Gene Expression Variations
por: Jung, Hyeim, et al.
Publicado: (2015)

Investigation of Splicing Quantitative Trait Loci in Arabidopsis thaliana
por: Yoo, Wonseok, et al.
Publicado: (2016)

Significance of functional disease-causal/susceptible variants identified by whole-genome analyses for the understanding of human diseases
por: HITOMI, Yuki, et al.
Publicado: (2017)

Beyond genomics: understanding exposotypes through metabolomics
por: Rattray, Nicholas J. W., et al.
Publicado: (2018)

Transcriptome analysis of alternative splicing in the pathogen life cycle in human foreskin fibroblasts infected with Trypanosoma cruzi
por: Jung, Hyeim, et al.
Publicado: (2020)

Epigenetic interplay between methylation and miRNA in bladder cancer: focus on isoform expression
por: Shivakumar, Manu, et al.
Publicado: (2021)

Alternative Splicing Regulation of Low-Frequency Genetic Variants in Exon 2 of TREM2 in Alzheimer’s Disease by Splicing-Based Aggregation
por: Han, Seonggyun, et al.
Publicado: (2021)

Brain Region-Dependent Alternative Splicing of Alzheimer Disease (AD)-Risk Genes Is Associated With Neuropathological Features in AD
por: Kim, Sara, et al.
Publicado: (2022)

Alternative Splicing Regulation of an Alzheimer’s Risk Variant in CLU
por: Han, Seonggyun, et al.
Publicado: (2020)

Understanding Human Variation in Infectious Disease Susceptibility through Clinical and Cellular GWAS
por: Ko, Dennis C., et al.
Publicado: (2013)

Understanding Regulatory Mechanisms of Brain Function and Disease through 3D Genome Organization
por: Liu, Weifang, et al.
Publicado: (2022)

Genome-wide Epigenetic Data Facilitate Understanding of Disease Susceptibility Association Studies
por: Hardison, Ross C.
Publicado: (2012)

Understanding pneumococcal serotype 1 biology through population genomic analysis
por: Chaguza, Chrispin, et al.
Publicado: (2016)

Pharmacogenomics of statins: understanding susceptibility to adverse effects
por: Kitzmiller, Joseph P, et al.
Publicado: (2016)

Modern approaches to understanding stress and disease susceptibility: A review with special emphasis on respiratory disease
por: Aich, Palok, et al.
Publicado: (2009)

Obesity genomics: assessing the transferability of susceptibility loci across diverse populations
por: Lu, Yingchang, et al.
Publicado: (2013)

Genetic variation affecting exon skipping contributes to brain structural atrophy in Alzheimer’s disease
por: Lee, Younghee, et al.
Publicado: (2018)

Understanding the Potential of Genome Editing in Parkinson’s Disease
por: Arango, David, et al.
Publicado: (2021)

Genomic Approach to Understand the Association of DNA Repair with Longevity and Healthy Aging Using Genomic Databases of Oldest-Old Population
por: Kim, Yeo Jin, et al.
Publicado: (2018)

Single-cell genomics to understand disease pathogenesis
por: Nomura, Seitaro
Publicado: (2020)

Rats: gnawing through the barriers to understanding genetic susceptibility and breast cancer
por: Blackburn, Anneke C
Publicado: (2011)

The case for increasing diversity in tissue-based functional genomics datasets to understand human disease susceptibility
por: Long, Erping, et al.
Publicado: (2022)

Genomic Variations in Susceptibility to Intracranial Aneurysm in the Korean Population
por: Hong, Eun Pyo, et al.
Publicado: (2019)

Advancing our understanding of functional genome organisation through studies in the fission yeast
por: Olsson, Ida, et al.
Publicado: (2010)

Using genetically isolated populations to understand the genomic basis of disease
por: Zeggini, Eleftheria
Publicado: (2014)

Exploring Eimeria Genomes to Understand Population Biology: Recent Progress and Future Opportunities
por: Blake, Damer P., et al.
Publicado: (2020)

Genome-Wide Identification of Susceptibility Alleles for Viral Infections through a Population Genetics Approach
por: Fumagalli, Matteo, et al.
Publicado: (2010)

Applying an evolutionary mismatch framework to understand disease susceptibility
por: Lea, Amanda J., et al.
Publicado: (2023)

The genetic backbone of ankylosing spondylitis: how knowledge of genetic susceptibility informs our understanding and management of disease
por: Kenyon, Marcus, et al.
Publicado: (2022)

ADAS-viewer: web-based application for integrative analysis of multi-omics data in Alzheimer’s disease
por: Han, Seonggyun, et al.
Publicado: (2021)

Genomics-driven drug discovery based on disease-susceptibility genes
por: Sonehara, Kyuto, et al.
Publicado: (2021)

Advances in the genome-wide association study of chronic hepatitis B susceptibility in Asian population
por: Qiu, Bing, et al.
Publicado: (2017)

The landscape of alternative splicing in HIV-1 infected CD4 T-cells
por: Byun, Seyoun, et al.
Publicado: (2020)

Genomic analysis of Korean patients with advanced prostate cancer by use of a comprehensive next-generation sequencing panel and low-coverage, whole-genome sequencing
por: Kang, Minyong, et al.
Publicado: (2019)

Identification of exon skipping events associated with Alzheimer’s disease in the human hippocampus
por: Han, Seonggyun, et al.
Publicado: (2019)

Compiling Multicopy Single-Stranded DNA Sequences from Bacterial Genome Sequences
por: Yoo, Wonseok, et al.
Publicado: (2016)

Integrating lipidomics and genomics: emerging tools to understand cardiovascular diseases
por: Tabassum, Rubina, et al.
Publicado: (2021)

Gene-set based genome-wide association analysis for the speed of sound in two skeletal sites of Korean women
por: Kwon, Ji-Sun, et al.
Publicado: (2014)

A methodology for multivariate phenotype-based genome-wide association studies to mine pleiotropic genes
por: Park, Sung Hee, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_jsti89nadgbc1pio393oc27nkm