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Neck circumference correlates with tumor size and lateral lymph node metastasis in men with small papillary thyroid carcinoma

BACKGROUND/AIMS: Obesity is correlated with numerous diseases, including thyroid cancer, but the clinical significance of obesity with regard to the clinical characteristics of thyroid cancer remains unclear. Neck circumference is an index of upper-body adipose tissue distribution. METHODS: In total...

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Autores principales: Kim, Mi Ra, Kim, Sang Soo, Huh, Jung Eun, Lee, Byung Joo, Lee, Jin Choon, Jeon, Yun Kyung, Kim, Bo Hyun, Kim, Seong Jang, Wang, Soo Geun, Kim, Yong Ki, Kim, In Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543962/
https://www.ncbi.nlm.nih.gov/pubmed/23345998
http://dx.doi.org/10.3904/kjim.2013.28.1.62
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author Kim, Mi Ra
Kim, Sang Soo
Huh, Jung Eun
Lee, Byung Joo
Lee, Jin Choon
Jeon, Yun Kyung
Kim, Bo Hyun
Kim, Seong Jang
Wang, Soo Geun
Kim, Yong Ki
Kim, In Joo
author_facet Kim, Mi Ra
Kim, Sang Soo
Huh, Jung Eun
Lee, Byung Joo
Lee, Jin Choon
Jeon, Yun Kyung
Kim, Bo Hyun
Kim, Seong Jang
Wang, Soo Geun
Kim, Yong Ki
Kim, In Joo
author_sort Kim, Mi Ra
collection PubMed
description BACKGROUND/AIMS: Obesity is correlated with numerous diseases, including thyroid cancer, but the clinical significance of obesity with regard to the clinical characteristics of thyroid cancer remains unclear. Neck circumference is an index of upper-body adipose tissue distribution. METHODS: In total, 401 patients with papillary thyroid carcinoma (PTC) measuring ≤ 2 cm were included. Neck circumference was measured horizontally at the level just below the thyroid cartilage on preoperative neck computed tomographic images. RESULTS: Neck circumference correlated significantly with tumor size in men (p = 0.001) but not in women (p = 0.930). Body mass index (BMI) did not significantly correlate with tumor size in either sex. Neck circumference was significantly larger in men with lateral lymph node (LN) metastasis than in those without (p = 0.004). Neck circumference and BMI did not differ significantly in women according to other factors such as tumor size, multifocality, extrathyroid extension, and LN metastasis. Tumor size and the prevalence of lateral LN metastasis in men tended to increase in the middle/large neck circumference subgroup compared with those in the low neck circumference subgroup. Multivariate logistic regression analysis revealed that neck circumference (p = 0.009) was a predictor for the presence of lateral LN metastasis in men. BMI was not a predictive factor for lateral LN involvement in either sex. CONCLUSIONS: Neck circumference, an indicator of central or visceral obesity but not BMI, may be associated with some prognostic factors in men with small PTC.
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spelling pubmed-35439622013-01-23 Neck circumference correlates with tumor size and lateral lymph node metastasis in men with small papillary thyroid carcinoma Kim, Mi Ra Kim, Sang Soo Huh, Jung Eun Lee, Byung Joo Lee, Jin Choon Jeon, Yun Kyung Kim, Bo Hyun Kim, Seong Jang Wang, Soo Geun Kim, Yong Ki Kim, In Joo Korean J Intern Med Original Article BACKGROUND/AIMS: Obesity is correlated with numerous diseases, including thyroid cancer, but the clinical significance of obesity with regard to the clinical characteristics of thyroid cancer remains unclear. Neck circumference is an index of upper-body adipose tissue distribution. METHODS: In total, 401 patients with papillary thyroid carcinoma (PTC) measuring ≤ 2 cm were included. Neck circumference was measured horizontally at the level just below the thyroid cartilage on preoperative neck computed tomographic images. RESULTS: Neck circumference correlated significantly with tumor size in men (p = 0.001) but not in women (p = 0.930). Body mass index (BMI) did not significantly correlate with tumor size in either sex. Neck circumference was significantly larger in men with lateral lymph node (LN) metastasis than in those without (p = 0.004). Neck circumference and BMI did not differ significantly in women according to other factors such as tumor size, multifocality, extrathyroid extension, and LN metastasis. Tumor size and the prevalence of lateral LN metastasis in men tended to increase in the middle/large neck circumference subgroup compared with those in the low neck circumference subgroup. Multivariate logistic regression analysis revealed that neck circumference (p = 0.009) was a predictor for the presence of lateral LN metastasis in men. BMI was not a predictive factor for lateral LN involvement in either sex. CONCLUSIONS: Neck circumference, an indicator of central or visceral obesity but not BMI, may be associated with some prognostic factors in men with small PTC. The Korean Association of Internal Medicine 2013-01 2012-12-28 /pmc/articles/PMC3543962/ /pubmed/23345998 http://dx.doi.org/10.3904/kjim.2013.28.1.62 Text en Copyright © 2013 The Korean Association of Internal Medicine http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kim, Mi Ra
Kim, Sang Soo
Huh, Jung Eun
Lee, Byung Joo
Lee, Jin Choon
Jeon, Yun Kyung
Kim, Bo Hyun
Kim, Seong Jang
Wang, Soo Geun
Kim, Yong Ki
Kim, In Joo
Neck circumference correlates with tumor size and lateral lymph node metastasis in men with small papillary thyroid carcinoma
title Neck circumference correlates with tumor size and lateral lymph node metastasis in men with small papillary thyroid carcinoma
title_full Neck circumference correlates with tumor size and lateral lymph node metastasis in men with small papillary thyroid carcinoma
title_fullStr Neck circumference correlates with tumor size and lateral lymph node metastasis in men with small papillary thyroid carcinoma
title_full_unstemmed Neck circumference correlates with tumor size and lateral lymph node metastasis in men with small papillary thyroid carcinoma
title_short Neck circumference correlates with tumor size and lateral lymph node metastasis in men with small papillary thyroid carcinoma
title_sort neck circumference correlates with tumor size and lateral lymph node metastasis in men with small papillary thyroid carcinoma
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543962/
https://www.ncbi.nlm.nih.gov/pubmed/23345998
http://dx.doi.org/10.3904/kjim.2013.28.1.62
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