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Identification of small molecules that Enhance Synaptogenesis using Synapse Microarrays
Synaptic function is affected in many brain diseases and disorders. Technologies for large-scale synapse assays can facilitate identification of drug leads. Here we report a “synapse microarray” technology that enables ultra-sensitive, high-throughput, and quantitative screening of synaptogenesis. O...
Autores principales: | Shi, Peng, Scott, Mark A, Ghosh, Balaram, Wan, Dongpeng, Wissner-Gross, Zachary, Mazitschek, Ralph, Haggarty, Stephen J., Yanik, Mehmet Fatih |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544154/ https://www.ncbi.nlm.nih.gov/pubmed/22027590 http://dx.doi.org/10.1038/ncomms1518 |
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