The Therapeutic Benefit of Allopurinol in the Treatment of Foreign Body Granulomas Caused by Polymethylmethacrylate Microspheres

Injectable polymethylmethacrylate (PMMA) microspheres are nonbiodegradable and too large for macrophage phagocytosis. There are several complications possible to happen, like chronic nonspecific inflammatory reactions, lip stiffness, infection, and granulomas. The occurrence of granulomas can lead t...

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Detalles Bibliográficos
Autores principales: de Barros Silveira, Luisa Kelmer Côrtes, de Oliveira, Felipe Ladeira, Alves, Thais de Barros Castro, Rambaldi, Maria Lourdes Candela, de Andrade, Felipe Cupertino, Kelmer, Santuzza de Carvalho, Barbosa, Fabio Cuiabano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544257/
https://www.ncbi.nlm.nih.gov/pubmed/23326688
http://dx.doi.org/10.1155/2012/945205
Descripción
Sumario:Injectable polymethylmethacrylate (PMMA) microspheres are nonbiodegradable and too large for macrophage phagocytosis. There are several complications possible to happen, like chronic nonspecific inflammatory reactions, lip stiffness, infection, and granulomas. The occurrence of granulomas can lead to a not aesthetic result, making some extreme changes in the patient's life. The objective of this case report is to describe the successful treatment of foreign body granulomas caused by polymethylmethacrylate microspheres using allopurinol, an innovative therapy for this condition.

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