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DNA Ligase-Mediated Translation of DNA Into Densely Functionalized Nucleic Acid Polymers
[Image: see text] We developed a method to translate DNA sequences into densely functionalized nucleic acids by using T4 DNA ligase to mediate the DNA-templated polymerization of 5′-phosphorylated trinucleotides containing a wide variety of appended functional groups. This polymerization proceeds se...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544274/ https://www.ncbi.nlm.nih.gov/pubmed/23256841 http://dx.doi.org/10.1021/ja311331m |