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Modulation of CXCL-8 expression in human melanoma cells regulates tumor growth, angiogenesis, invasion, and metastasis

CXCL-8, a chemokine secreted by melanoma and stromal cells, serves as a growth and angiogenic factor for melanoma progression. This study evaluated how modulation of CXCL-8 levels in melanoma cell lines with different tumorigenic and metastatic potentials affected multiple tumor phenotypes. A375P ce...

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Detalles Bibliográficos
Autores principales: Wu, Sheng, Singh, Seema, Varney, Michelle L, Kindle, Scott, Singh, Rakesh K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544458/
https://www.ncbi.nlm.nih.gov/pubmed/23342280
http://dx.doi.org/10.1002/cam4.28

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