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Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate

BACKGROUND: To study the role of microRNA (miRNA) in the regulation of Chinese hamster ovary (CHO) cell growth, qPCR, microarray and quantitative LC-MS/MS analysis were utilised for simultaneous expression profiling of miRNA, mRNA and protein. The sample set under investigation consisted of clones w...

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Detalles Bibliográficos
Autores principales: Clarke, Colin, Henry, Michael, Doolan, Padraig, Kelly, Shane, Aherne, Sinead, Sanchez, Noelia, Kelly, Paul, Kinsella, Paula, Breen, Laura, Madden, Stephen F, Zhang, Lin, Leonard, Mark, Clynes, Martin, Meleady, Paula, Barron, Niall
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544584/
https://www.ncbi.nlm.nih.gov/pubmed/23170974
http://dx.doi.org/10.1186/1471-2164-13-656