Cargando…

Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate

BACKGROUND: To study the role of microRNA (miRNA) in the regulation of Chinese hamster ovary (CHO) cell growth, qPCR, microarray and quantitative LC-MS/MS analysis were utilised for simultaneous expression profiling of miRNA, mRNA and protein. The sample set under investigation consisted of clones w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Clarke, Colin, Henry, Michael, Doolan, Padraig, Kelly, Shane, Aherne, Sinead, Sanchez, Noelia, Kelly, Paul, Kinsella, Paula, Breen, Laura, Madden, Stephen F, Zhang, Lin, Leonard, Mark, Clynes, Martin, Meleady, Paula, Barron, Niall
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544584/ https://www.ncbi.nlm.nih.gov/pubmed/23170974 http://dx.doi.org/10.1186/1471-2164-13-656

Ejemplares similares

Parallel mRNA, proteomics and miRNA expression analysis in cell line models of the intestine
por: O’Sullivan, Finbarr, et al.
Publicado: (2017)

MiR-7 Triggers Cell Cycle Arrest at the G1/S Transition by Targeting Multiple Genes Including Skp2 and Psme3
por: Sanchez, Noelia, et al.
Publicado: (2013)

Engineering CHO cell growth by stable manipulation of miRNA expression
por: Sanchez, Noëlia, et al.
Publicado: (2011)

Sustained productivity in recombinant Chinese Hamster Ovary (CHO) cell lines: proteome analysis of the molecular basis for a process-related phenotype
por: Meleady, Paula, et al.
Publicado: (2011)

Differential expression of miRNAs and functional role of mir-200a in high and low productivity CHO cells expressing an Fc fusion protein
por: Bryan, Laura, et al.
Publicado: (2021)

Differential protein expression following low temperature culture of suspension CHO-K1 cells
por: Kumar, Niraj, et al.
Publicado: (2008)

Gene expression changes as markers of early lapatinib response in a panel of breast cancer cell lines
por: O’Neill, Fiona, et al.
Publicado: (2012)

A gene expression profile indicative of early stage HER2 targeted therapy response
por: O’Neill, Fiona, et al.
Publicado: (2013)

Mapping the molecular basis for growth related phenotypes in industrial producer CHO cell lines using differential proteomic analysis
por: Bryan, Laura, et al.
Publicado: (2021)

Genomic Profiling and Functional Analysis of let-7c miRNA-mRNA Interactions Identify SOX13 to Be Involved in Invasion and Progression of Pancreatic Cancer
por: Nelson, Shannon R., et al.
Publicado: (2020)

Acute exposure to organic and inorganic sources of copper: Differential response in intestinal cell lines
por: Keenan, Joanne, et al.
Publicado: (2018)

Proteomic differences in recombinant CHO cells producing two similar antibody fragments
por: Sommeregger, Wolfgang, et al.
Publicado: (2016)

A proteomic profiling dataset of recombinant Chinese hamster ovary cells showing enhanced cellular growth following miR-378 depletion
por: Coleman, Orla, et al.
Publicado: (2018)

CHO microRNA engineering is growing up: Recent successes and future challenges()
por: Jadhav, Vaibhav, et al.
Publicado: (2013)

Circulating miRNAs miR-34a and miR-150 associated with colorectal cancer progression
por: Aherne, Sinéad T, et al.
Publicado: (2015)

Integrative Analysis of miRNA-mRNA and miRNA-miRNA Interactions
por: Guo, Li, et al.
Publicado: (2014)

SNIP/p140Cap mRNA expression is an unfavourable prognostic factor in breast cancer and is not expressed in normal breast tissue
por: Kennedy, S, et al.
Publicado: (2008)

Label-Free Quantitative Proteomics Analysis of Adriamycin Selected Multidrug Resistant Human Lung Cancer Cells
por: Efeoglu, Esen, et al.
Publicado: (2022)

BreastMark: An Integrated Approach to Mining Publicly Available Transcriptomic Datasets Relating to Breast Cancer Outcome
por: Madden, Stephen F, et al.
Publicado: (2013)

Quantification of miRNA-mRNA Interactions
por: Muniategui, Ander, et al.
Publicado: (2012)

Discovering the ‘Dark matters’ in expression data of miRNA based on the miRNA-mRNA and miRNA-lncRNA networks
por: Pian, Cong, et al.
Publicado: (2018)

Dynamic miRNA–mRNA paradigms: New faces of miRNAs
por: Ni, Wen-Juan, et al.
Publicado: (2015)

Improving miRNA-mRNA interaction predictions
por: Tabas-Madrid, Daniel, et al.
Publicado: (2014)

Integrated miRNA and mRNA expression profiling to identify mRNA targets of dysregulated miRNAs in pulmonary tuberculosis
por: Zhang, Xing, et al.
Publicado: (2018)

MMpred: functional miRNA – mRNA interaction analyses by miRNA expression prediction
por: Stempor, Przemyslaw A, et al.
Publicado: (2012)

Integrative bioinformatics analysis of miRNA and mRNA expression profiles and identification of associated miRNA-mRNA network in aortic dissection
por: Su, Yiming, et al.
Publicado: (2019)

Bioinformatics analysis of mRNA and miRNA microarray to identify the key miRNA-mRNA pairs in cisplatin-resistant ovarian cancer
por: Xue, Bai, et al.
Publicado: (2021)

Integrating miRNA and mRNA Profiling to Assess the Potential miRNA–mRNA Modules Linked With Testicular Immune Homeostasis in Sheep
por: Li, Taotao, et al.
Publicado: (2021)

Alterations in hepatic miRNA expression during negative energy balance in postpartum dairy cattle
por: Fatima, Attia, et al.
Publicado: (2014)

Integrated miRNA and mRNA expression profiling to identify mRNA targets of dysregulated miRNAs in non-obstructive azoospermia
por: Zhuang, Xuan, et al.
Publicado: (2015)

miRNA and mRNA expression analysis reveals potential sex-biased miRNA expression
por: Guo, Li, et al.
Publicado: (2017)

Interplay of Cellular mRNA, miRNA and Viral miRNA during Infection of a Cell
por: Zhdanov, Vladimir P.
Publicado: (2022)

Integrated ordination of miRNA and mRNA expression profiles
por: Diaz, Giacomo, et al.
Publicado: (2015)

miRNA–mRNA Associated With Survival in Endometrial Cancer
por: Xu, Xiaofeng, et al.
Publicado: (2019)

A holistic miRNA-mRNA module discovery
por: Shommo, Ghada, et al.
Publicado: (2021)

Regulatory miRNA–mRNA Networks in Parkinson’s Disease
por: Santos-Lobato, Bruno Lopes, et al.
Publicado: (2021)

Paired miRNA- and messenger RNA-sequencing identifies novel miRNA-mRNA interactions in multiple myeloma
por: Aass, Kristin Roseth, et al.
Publicado: (2022)

Crosstalk Among circRNA/lncRNA, miRNA, and mRNA in Osteoarthritis
por: Kong, Hui, et al.
Publicado: (2021)

Impact of probe annotation on the integration of miRNA–mRNA expression profiles for miRNA target detection
por: Sales, Gabriele, et al.
Publicado: (2010)

Single‐cell mRNA profiling reveals the hierarchical response of miRNA targets to miRNA induction
por: Rzepiela, Andrzej J, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_2l3sehgo2sl28hogj2v282b0mm