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Delirium in postoperative nonventilated intensive care patients: risk factors and outcomes
BACKGROUND: Delirium features can vary greatly depending on the postoperative population studied; however, most studies focus only on high-risk patients. Describing the impact of delirium and risk factors in mixed populations can help in the development of preventive actions. METHODS: The occurrence...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544687/ https://www.ncbi.nlm.nih.gov/pubmed/23272945 http://dx.doi.org/10.1186/2110-5820-2-51 |
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author | Serafim, Rodrigo Bernardo Dutra, Maximiliano F Saddy, Felipe Tura, Bernardo de Castro, Jose Eduardo Couto Villarinho, Luciana C da Gloria Santos, Maria Bozza, Fernando Augusto Rocco, José Rodolfo |
author_facet | Serafim, Rodrigo Bernardo Dutra, Maximiliano F Saddy, Felipe Tura, Bernardo de Castro, Jose Eduardo Couto Villarinho, Luciana C da Gloria Santos, Maria Bozza, Fernando Augusto Rocco, José Rodolfo |
author_sort | Serafim, Rodrigo Bernardo |
collection | PubMed |
description | BACKGROUND: Delirium features can vary greatly depending on the postoperative population studied; however, most studies focus only on high-risk patients. Describing the impact of delirium and risk factors in mixed populations can help in the development of preventive actions. METHODS: The occurrence of delirium was evaluated prospectively in 465 consecutive nonventilated postoperative patients admitted to a surgical intensive care unit (SICU) using the confusion assessment method (CAM). Patients with and without delirium were compared. A multiple logistic regression was performed to identify the main risk factors for delirium in the first 24 h of admission to the SICU and the main predictors of outcomes. RESULTS: Delirium was diagnosed in 43 (9.2%) individuals and was more frequent on the second and third days of admission. The presence of delirium resulted in longer lengths of SICU and hospital stays [6 days (3–13) vs. 2 days (1–3), p < 0.001 and 26 days (12–39) vs. 6 days (3–13), p <0.001, respectively], as well as higher hospital and SICU mortality rates [16.3% vs. 4.0%, p = 0.004 and 6.5% vs. 1.7%, p = 0.042, respectively]. The risk factors for delirium were age (odds ratio (OR), 1.04 [1.02-1.07]), Acute Physiologic Score (APS; OR, 1.11 [1.04-1.2]), emergency surgery (OR, 8.05 [3.58-18.06]), the use of benzodiazepines (OR, 2.28 [1.04-5.00]), and trauma (OR, 6.16 [4.1-6.5]). CONCLUSIONS: Delirium negatively impacts postoperative nonventilated patients. Risk factors can be used to detect high-risk patients in a mixed population of SICU patients. |
format | Online Article Text |
id | pubmed-3544687 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Springer |
record_format | MEDLINE/PubMed |
spelling | pubmed-35446872013-01-15 Delirium in postoperative nonventilated intensive care patients: risk factors and outcomes Serafim, Rodrigo Bernardo Dutra, Maximiliano F Saddy, Felipe Tura, Bernardo de Castro, Jose Eduardo Couto Villarinho, Luciana C da Gloria Santos, Maria Bozza, Fernando Augusto Rocco, José Rodolfo Ann Intensive Care Research BACKGROUND: Delirium features can vary greatly depending on the postoperative population studied; however, most studies focus only on high-risk patients. Describing the impact of delirium and risk factors in mixed populations can help in the development of preventive actions. METHODS: The occurrence of delirium was evaluated prospectively in 465 consecutive nonventilated postoperative patients admitted to a surgical intensive care unit (SICU) using the confusion assessment method (CAM). Patients with and without delirium were compared. A multiple logistic regression was performed to identify the main risk factors for delirium in the first 24 h of admission to the SICU and the main predictors of outcomes. RESULTS: Delirium was diagnosed in 43 (9.2%) individuals and was more frequent on the second and third days of admission. The presence of delirium resulted in longer lengths of SICU and hospital stays [6 days (3–13) vs. 2 days (1–3), p < 0.001 and 26 days (12–39) vs. 6 days (3–13), p <0.001, respectively], as well as higher hospital and SICU mortality rates [16.3% vs. 4.0%, p = 0.004 and 6.5% vs. 1.7%, p = 0.042, respectively]. The risk factors for delirium were age (odds ratio (OR), 1.04 [1.02-1.07]), Acute Physiologic Score (APS; OR, 1.11 [1.04-1.2]), emergency surgery (OR, 8.05 [3.58-18.06]), the use of benzodiazepines (OR, 2.28 [1.04-5.00]), and trauma (OR, 6.16 [4.1-6.5]). CONCLUSIONS: Delirium negatively impacts postoperative nonventilated patients. Risk factors can be used to detect high-risk patients in a mixed population of SICU patients. Springer 2012-12-31 /pmc/articles/PMC3544687/ /pubmed/23272945 http://dx.doi.org/10.1186/2110-5820-2-51 Text en Copyright ©2012 Serafim et al.; licensee Springer. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Serafim, Rodrigo Bernardo Dutra, Maximiliano F Saddy, Felipe Tura, Bernardo de Castro, Jose Eduardo Couto Villarinho, Luciana C da Gloria Santos, Maria Bozza, Fernando Augusto Rocco, José Rodolfo Delirium in postoperative nonventilated intensive care patients: risk factors and outcomes |
title | Delirium in postoperative nonventilated intensive care patients: risk factors and outcomes |
title_full | Delirium in postoperative nonventilated intensive care patients: risk factors and outcomes |
title_fullStr | Delirium in postoperative nonventilated intensive care patients: risk factors and outcomes |
title_full_unstemmed | Delirium in postoperative nonventilated intensive care patients: risk factors and outcomes |
title_short | Delirium in postoperative nonventilated intensive care patients: risk factors and outcomes |
title_sort | delirium in postoperative nonventilated intensive care patients: risk factors and outcomes |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544687/ https://www.ncbi.nlm.nih.gov/pubmed/23272945 http://dx.doi.org/10.1186/2110-5820-2-51 |
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