The possible mechanisms of CYP2E1 interactions with HSP90 and the influence of ethanol on them

BACKGROUND: Microsomal CYP2E1 metabolizes about 160 hydrophobic exogens, many of which are environmental pollutants. While metabolising xenobiotics CYP2E1 on one hand facilitates in their excretion and on the other hand activates them into the cytotoxins, which may damage the cell. Thus the CYP2E1 a...

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Detalles Bibliográficos
Autores principales: Kitam, Volodymyr O, Maksymchuk, Oksana V, Chashchyn, Mykola O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544703/
https://www.ncbi.nlm.nih.gov/pubmed/23241420
http://dx.doi.org/10.1186/1472-6807-12-33

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544703/
https://www.ncbi.nlm.nih.gov/pubmed/23241420
http://dx.doi.org/10.1186/1472-6807-12-33

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