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The possible mechanisms of CYP2E1 interactions with HSP90 and the influence of ethanol on them
BACKGROUND: Microsomal CYP2E1 metabolizes about 160 hydrophobic exogens, many of which are environmental pollutants. While metabolising xenobiotics CYP2E1 on one hand facilitates in their excretion and on the other hand activates them into the cytotoxins, which may damage the cell. Thus the CYP2E1 a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544703/ https://www.ncbi.nlm.nih.gov/pubmed/23241420 http://dx.doi.org/10.1186/1472-6807-12-33 |