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The History of Slavs Inferred from Complete Mitochondrial Genome Sequences

To shed more light on the processes leading to crystallization of a Slavic identity, we investigated variability of complete mitochondrial genomes belonging to haplogroups H5 and H6 (63 mtDNA genomes) from the populations of Eastern and Western Slavs, including new samples of Poles, Ukrainians and C...

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Autores principales: Mielnik-Sikorska, Marta, Daca, Patrycja, Malyarchuk, Boris, Derenko, Miroslava, Skonieczna, Katarzyna, Perkova, Maria, Dobosz, Tadeusz, Grzybowski, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544712/
https://www.ncbi.nlm.nih.gov/pubmed/23342138
http://dx.doi.org/10.1371/journal.pone.0054360
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author Mielnik-Sikorska, Marta
Daca, Patrycja
Malyarchuk, Boris
Derenko, Miroslava
Skonieczna, Katarzyna
Perkova, Maria
Dobosz, Tadeusz
Grzybowski, Tomasz
author_facet Mielnik-Sikorska, Marta
Daca, Patrycja
Malyarchuk, Boris
Derenko, Miroslava
Skonieczna, Katarzyna
Perkova, Maria
Dobosz, Tadeusz
Grzybowski, Tomasz
author_sort Mielnik-Sikorska, Marta
collection PubMed
description To shed more light on the processes leading to crystallization of a Slavic identity, we investigated variability of complete mitochondrial genomes belonging to haplogroups H5 and H6 (63 mtDNA genomes) from the populations of Eastern and Western Slavs, including new samples of Poles, Ukrainians and Czechs presented here. Molecular dating implies formation of H5 approximately 11.5–16 thousand years ago (kya) in the areas of southern Europe. Within ancient haplogroup H6, dated at around 15–28 kya, there is a subhaplogroup H6c, which probably survived the last glaciation in Europe and has undergone expansion only 3–4 kya, together with the ancestors of some European groups, including the Slavs, because H6c has been detected in Czechs, Poles and Slovaks. Detailed analysis of complete mtDNAs allowed us to identify a number of lineages that seem specific for Central and Eastern Europe (H5a1f, H5a2, H5a1r, H5a1s, H5b4, H5e1a, H5u1, some subbranches of H5a1a and H6a1a9). Some of them could possibly be traced back to at least ∼4 kya, which indicates that some of the ancestors of today's Slavs (Poles, Czechs, Slovaks, Ukrainians and Russians) inhabited areas of Central and Eastern Europe much earlier than it was estimated on the basis of archaeological and historical data. We also sequenced entire mitochondrial genomes of several non-European lineages (A, C, D, G, L) found in contemporary populations of Poland and Ukraine. The analysis of these haplogroups confirms the presence of Siberian (C5c1, A8a1) and Ashkenazi-specific (L2a1l2a) mtDNA lineages in Slavic populations. Moreover, we were able to pinpoint some lineages which could possibly reflect the relatively recent contacts of Slavs with nomadic Altaic peoples (C4a1a, G2a, D5a2a1a1).
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spelling pubmed-35447122013-01-22 The History of Slavs Inferred from Complete Mitochondrial Genome Sequences Mielnik-Sikorska, Marta Daca, Patrycja Malyarchuk, Boris Derenko, Miroslava Skonieczna, Katarzyna Perkova, Maria Dobosz, Tadeusz Grzybowski, Tomasz PLoS One Research Article To shed more light on the processes leading to crystallization of a Slavic identity, we investigated variability of complete mitochondrial genomes belonging to haplogroups H5 and H6 (63 mtDNA genomes) from the populations of Eastern and Western Slavs, including new samples of Poles, Ukrainians and Czechs presented here. Molecular dating implies formation of H5 approximately 11.5–16 thousand years ago (kya) in the areas of southern Europe. Within ancient haplogroup H6, dated at around 15–28 kya, there is a subhaplogroup H6c, which probably survived the last glaciation in Europe and has undergone expansion only 3–4 kya, together with the ancestors of some European groups, including the Slavs, because H6c has been detected in Czechs, Poles and Slovaks. Detailed analysis of complete mtDNAs allowed us to identify a number of lineages that seem specific for Central and Eastern Europe (H5a1f, H5a2, H5a1r, H5a1s, H5b4, H5e1a, H5u1, some subbranches of H5a1a and H6a1a9). Some of them could possibly be traced back to at least ∼4 kya, which indicates that some of the ancestors of today's Slavs (Poles, Czechs, Slovaks, Ukrainians and Russians) inhabited areas of Central and Eastern Europe much earlier than it was estimated on the basis of archaeological and historical data. We also sequenced entire mitochondrial genomes of several non-European lineages (A, C, D, G, L) found in contemporary populations of Poland and Ukraine. The analysis of these haplogroups confirms the presence of Siberian (C5c1, A8a1) and Ashkenazi-specific (L2a1l2a) mtDNA lineages in Slavic populations. Moreover, we were able to pinpoint some lineages which could possibly reflect the relatively recent contacts of Slavs with nomadic Altaic peoples (C4a1a, G2a, D5a2a1a1). Public Library of Science 2013-01-14 /pmc/articles/PMC3544712/ /pubmed/23342138 http://dx.doi.org/10.1371/journal.pone.0054360 Text en © 2013 Mielnik-Sikorska et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Mielnik-Sikorska, Marta
Daca, Patrycja
Malyarchuk, Boris
Derenko, Miroslava
Skonieczna, Katarzyna
Perkova, Maria
Dobosz, Tadeusz
Grzybowski, Tomasz
The History of Slavs Inferred from Complete Mitochondrial Genome Sequences
title The History of Slavs Inferred from Complete Mitochondrial Genome Sequences
title_full The History of Slavs Inferred from Complete Mitochondrial Genome Sequences
title_fullStr The History of Slavs Inferred from Complete Mitochondrial Genome Sequences
title_full_unstemmed The History of Slavs Inferred from Complete Mitochondrial Genome Sequences
title_short The History of Slavs Inferred from Complete Mitochondrial Genome Sequences
title_sort history of slavs inferred from complete mitochondrial genome sequences
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544712/
https://www.ncbi.nlm.nih.gov/pubmed/23342138
http://dx.doi.org/10.1371/journal.pone.0054360
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