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Establishment of HRAS(G12V) Transgenic Medaka as a Stable Tumor Model for In Vivo Screening of Anticancer Drugs
Most targeted anticancer drugs have been identified by screening at the molecular or cellular level in vitro. However, many compounds selected by such costly and time-consuming screening do not prove effective against tumors in vivo. The development of anticancer drugs would thus be facilitated by t...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544794/ https://www.ncbi.nlm.nih.gov/pubmed/23342156 http://dx.doi.org/10.1371/journal.pone.0054424 |