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CcpA-Independent Glucose Regulation of Lactate Dehydrogenase 1 in Staphylococcus aureus

Lactate Dehydrogenase 1 (Ldh1) is a key enzyme involved in Staphylococcus aureus NO·-resistance. Full ldh1-induction requires the presence of glucose, and mutants lacking the Carbon-Catabolite Protein (CcpA) exhibit decreased ldh1 transcription and diminished Ldh1 activity. The redox-regulator Rex r...

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Detalles Bibliográficos
Autores principales:	Crooke, Adrianne K., Fuller, James R., Obrist, Markus W., Tomkovich, Sarah E., Vitko, Nicholas P., Richardson, Anthony R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544828/ https://www.ncbi.nlm.nih.gov/pubmed/23342123 http://dx.doi.org/10.1371/journal.pone.0054293

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