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Laser Capture Microdissected Mucosa versus Whole Tissue Specimens for Assessment of Radiation-Induced Dynamic Molecular and Pathway Changes in the Small Intestine
BACKGROUND: The intestinal mucosa is the compartment that sustains the most severe injury in response to radiation and is therefore of primary interest. The use of whole gut extracts for analysis of gene expression may confound important changes in the mucosa. On the other hand, laser capture microd...
Autores principales: | Zheng, Junying, Garg, Sarita, Wang, Junru, Loose, David S., Hauer-Jensen, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544848/ https://www.ncbi.nlm.nih.gov/pubmed/23341980 http://dx.doi.org/10.1371/journal.pone.0053711 |
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