The Sesquiterpene Lactone Dehydroleucodine Triggers Senescence and Apoptosis in Association with Accumulation of DNA Damage Markers

Sesquiterpene lactones (SLs) are plant-derived compounds that display anti-cancer effects. Some SLs derivatives have a marked killing effect on cancer cells and have therefore reached clinical trials. Little is known regarding the mechanism of action of SLs. We studied the responses of human cancer...

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Detalles Bibliográficos
Autores principales: Costantino, Valeria V., Mansilla, Sabrina F., Speroni, Juliana, Amaya, Celina, Cuello-Carrión, Darío, Ciocca, Daniel R., Priestap, Horacio A., Barbieri, Manuel A., Gottifredi, Vanesa, Lopez, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544853/
https://www.ncbi.nlm.nih.gov/pubmed/23341930
http://dx.doi.org/10.1371/journal.pone.0053168

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