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MAIT Cell Recognition of MR1 on Bacterially Infected and Uninfected Cells

Mucosal-associated invariant T cells are a unique population of T cells that express a semi-invariant αβ TCR and are restricted by the MHC class I-related molecule MR1. MAIT cells recognize uncharacterized ligand(s) presented by MR1 through the cognate interaction between their TCR and MR1. To under...

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Detalles Bibliográficos
Autores principales: Young, Mary H., U’Ren, Lance, Huang, Shouxiong, Mallevaey, Thierry, Scott-Browne, James, Crawford, Frances, Lantz, Olivier, Hansen, Ted H., Kappler, John, Marrack, Philippa, Gapin, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544856/
https://www.ncbi.nlm.nih.gov/pubmed/23342002
http://dx.doi.org/10.1371/journal.pone.0053789