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Hsmar1 Transposition Is Sensitive to the Topology of the Transposon Donor and the Target
Hsmar1 is a member of the Tc1-mariner superfamily of DNA transposons. These elements mobilize within the genome of their host by a cut-and-paste mechanism. We have exploited the in vitro reaction provided by Hsmar1 to investigate the effect of DNA supercoiling on transposon integration. We found tha...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544897/ https://www.ncbi.nlm.nih.gov/pubmed/23341977 http://dx.doi.org/10.1371/journal.pone.0053690 |