Genetic Instability and Intratumoral Heterogeneity in Neuroblastoma with MYCN Amplification Plus 11q Deletion

BACKGROUND/AIM: Genetic analysis in neuroblastoma has identified the profound influence of MYCN amplification and 11q deletion in patients’ prognosis. These two features of high-risk neuroblastoma usually occur as mutually exclusive genetic markers, although in rare cases both are present in the sam...

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Detalles Bibliográficos
Autores principales: Villamón, Eva, Berbegall, Ana P., Piqueras, Marta, Tadeo, Irene, Castel, Victoria, Djos, Anna, Martinsson, Tommy, Navarro, Samuel, Noguera, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544899/
https://www.ncbi.nlm.nih.gov/pubmed/23341988
http://dx.doi.org/10.1371/journal.pone.0053740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544899/
https://www.ncbi.nlm.nih.gov/pubmed/23341988
http://dx.doi.org/10.1371/journal.pone.0053740

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