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Genetic Instability and Intratumoral Heterogeneity in Neuroblastoma with MYCN Amplification Plus 11q Deletion
BACKGROUND/AIM: Genetic analysis in neuroblastoma has identified the profound influence of MYCN amplification and 11q deletion in patients’ prognosis. These two features of high-risk neuroblastoma usually occur as mutually exclusive genetic markers, although in rare cases both are present in the sam...
Autores principales: | Villamón, Eva, Berbegall, Ana P., Piqueras, Marta, Tadeo, Irene, Castel, Victoria, Djos, Anna, Martinsson, Tommy, Navarro, Samuel, Noguera, Rosa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544899/ https://www.ncbi.nlm.nih.gov/pubmed/23341988 http://dx.doi.org/10.1371/journal.pone.0053740 |
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