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Solving Hard Computational Problems Efficiently: Asymptotic Parametric Complexity 3-Coloring Algorithm

Many practical problems in almost all scientific and technological disciplines have been classified as computationally hard (NP-hard or even NP-complete). In life sciences, combinatorial optimization problems frequently arise in molecular biology, e.g., genome sequencing; global alignment of multipl...

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Autor principal: Martín H., José Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544923/
https://www.ncbi.nlm.nih.gov/pubmed/23349711
http://dx.doi.org/10.1371/journal.pone.0053437
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author Martín H., José Antonio
author_facet Martín H., José Antonio
author_sort Martín H., José Antonio
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description Many practical problems in almost all scientific and technological disciplines have been classified as computationally hard (NP-hard or even NP-complete). In life sciences, combinatorial optimization problems frequently arise in molecular biology, e.g., genome sequencing; global alignment of multiple genomes; identifying siblings or discovery of dysregulated pathways. In almost all of these problems, there is the need for proving a hypothesis about certain property of an object that can be present if and only if it adopts some particular admissible structure (an NP-certificate) or be absent (no admissible structure), however, none of the standard approaches can discard the hypothesis when no solution can be found, since none can provide a proof that there is no admissible structure. This article presents an algorithm that introduces a novel type of solution method to “efficiently” solve the graph 3-coloring problem; an NP-complete problem. The proposed method provides certificates (proofs) in both cases: present or absent, so it is possible to accept or reject the hypothesis on the basis of a rigorous proof. It provides exact solutions and is polynomial-time (i.e., efficient) however parametric. The only requirement is sufficient computational power, which is controlled by the parameter [Image: see text]. Nevertheless, here it is proved that the probability of requiring a value of [Image: see text] to obtain a solution for a random graph decreases exponentially: [Image: see text], making tractable almost all problem instances. Thorough experimental analyses were performed. The algorithm was tested on random graphs, planar graphs and 4-regular planar graphs. The obtained experimental results are in accordance with the theoretical expected results.
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spelling pubmed-35449232013-01-24 Solving Hard Computational Problems Efficiently: Asymptotic Parametric Complexity 3-Coloring Algorithm Martín H., José Antonio PLoS One Research Article Many practical problems in almost all scientific and technological disciplines have been classified as computationally hard (NP-hard or even NP-complete). In life sciences, combinatorial optimization problems frequently arise in molecular biology, e.g., genome sequencing; global alignment of multiple genomes; identifying siblings or discovery of dysregulated pathways. In almost all of these problems, there is the need for proving a hypothesis about certain property of an object that can be present if and only if it adopts some particular admissible structure (an NP-certificate) or be absent (no admissible structure), however, none of the standard approaches can discard the hypothesis when no solution can be found, since none can provide a proof that there is no admissible structure. This article presents an algorithm that introduces a novel type of solution method to “efficiently” solve the graph 3-coloring problem; an NP-complete problem. The proposed method provides certificates (proofs) in both cases: present or absent, so it is possible to accept or reject the hypothesis on the basis of a rigorous proof. It provides exact solutions and is polynomial-time (i.e., efficient) however parametric. The only requirement is sufficient computational power, which is controlled by the parameter [Image: see text]. Nevertheless, here it is proved that the probability of requiring a value of [Image: see text] to obtain a solution for a random graph decreases exponentially: [Image: see text], making tractable almost all problem instances. Thorough experimental analyses were performed. The algorithm was tested on random graphs, planar graphs and 4-regular planar graphs. The obtained experimental results are in accordance with the theoretical expected results. Public Library of Science 2013-01-14 /pmc/articles/PMC3544923/ /pubmed/23349711 http://dx.doi.org/10.1371/journal.pone.0053437 Text en © 2013 José Antonio Martín H http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Martín H., José Antonio
Solving Hard Computational Problems Efficiently: Asymptotic Parametric Complexity 3-Coloring Algorithm
title Solving Hard Computational Problems Efficiently: Asymptotic Parametric Complexity 3-Coloring Algorithm
title_full Solving Hard Computational Problems Efficiently: Asymptotic Parametric Complexity 3-Coloring Algorithm
title_fullStr Solving Hard Computational Problems Efficiently: Asymptotic Parametric Complexity 3-Coloring Algorithm
title_full_unstemmed Solving Hard Computational Problems Efficiently: Asymptotic Parametric Complexity 3-Coloring Algorithm
title_short Solving Hard Computational Problems Efficiently: Asymptotic Parametric Complexity 3-Coloring Algorithm
title_sort solving hard computational problems efficiently: asymptotic parametric complexity 3-coloring algorithm
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544923/
https://www.ncbi.nlm.nih.gov/pubmed/23349711
http://dx.doi.org/10.1371/journal.pone.0053437
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