Association of inflammation with atrial fibrillation in hyperthyroidism

OBJECTIVES: The aim of this study was to evaluate the relationship between inflammation and development of atrial fibrillation (AF) in patients with hyperthyroidism. METHODS: A total of 65 patients with newly diagnosed hyperthyroidism, 35 of whom were in sinus rhythm and 30 of whom in AF. Thirty fiv...

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Detalles Bibliográficos
Autores principales: Ozaydin, Mehmet, Kutlucan, Ali, Turker, Yasin, Koroglu, Banu, Arslan, Akif, Uysal, Bayram A., Erdogan, Dogan, Varol, Ercan, Dogan, Abdullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545250/
https://www.ncbi.nlm.nih.gov/pubmed/23341838
http://dx.doi.org/10.3724/SP.J.1263.2012.06251
Descripción
Sumario:OBJECTIVES: The aim of this study was to evaluate the relationship between inflammation and development of atrial fibrillation (AF) in patients with hyperthyroidism. METHODS: A total of 65 patients with newly diagnosed hyperthyroidism, 35 of whom were in sinus rhythm and 30 of whom in AF. Thirty five age- and gender-matched patients in a control group were included in the study. Factors associated with the development of AF were evaluated by multivariate regression analysis. RESULTS: Factors associated with AF in multivariate analysis included high sensitivity C reactive protein (HsCRP) [odds ratio (OR): 11.19; 95% confidence interval (95% CI): 1.80-69.53; P = 0.003], free T4 (OR: 8.76; 95% CI: 2.09–36.7; P = 0.003), and left atrial diameter (OR: 1.25; 95% CI: 1.06–1.47; P = 0.008). CONCLUSIONS: The results of the present study suggest that HsCRP, an indicator of inflammation, free T4 and left atrial diameter are associated with the development AF in patients with hyperthyroidism.

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