Cargando…
A systems approach defining constraints of the genome architecture on lineage selection and evolvability during somatic cancer evolution
Most clinically distinguishable malignant tumors are characterized by specific mutations, specific patterns of chromosomal rearrangements and a predominant mechanism of genetic instability but it remains unsolved whether modifications of cancer genomes can be explained solely by mutations and select...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545268/ https://www.ncbi.nlm.nih.gov/pubmed/23336076 http://dx.doi.org/10.1242/bio.20122543 |