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Glucocorticoid Repression of Inflammatory Gene Expression Shows Differential Responsiveness by Transactivation- and Transrepression-Dependent Mechanisms
Binding of glucocorticoid to the glucocorticoid receptor (GR/NR3C1) may repress inflammatory gene transcription via direct, protein synthesis-independent processes (transrepression), or by activating transcription (transactivation) of multiple anti-inflammatory/repressive factors. Using human pulmon...
Autores principales: | King, Elizabeth M., Chivers, Joanna E., Rider, Christopher F., Minnich, Anne, Giembycz, Mark A., Newton, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545719/ https://www.ncbi.nlm.nih.gov/pubmed/23349769 http://dx.doi.org/10.1371/journal.pone.0053936 |
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