Differential effects of formoterol on thrombin- and PDGF-induced proliferation of human pulmonary arterial vascular smooth muscle cells

BACKGROUND: Increased pulmonary arterial vascular smooth muscle (PAVSM) cell proliferation is a key pathophysiological component of pulmonary vascular remodeling in pulmonary arterial hypertension (PH). The long-acting β(2)-adrenergic receptor (β(2)AR) agonist formoterol, a racemate comprised of (R,...

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Detalles Bibliográficos
Autores principales: Goncharova, Elena A, Khavin, Irene S, Goncharov, Dmitry A, Krymskaya, Vera P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545871/
https://www.ncbi.nlm.nih.gov/pubmed/23186269
http://dx.doi.org/10.1186/1465-9921-13-109

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