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A Polypeptide-DNA Hybrid with Selective Linking Capability Applied to Single Molecule Nano-Mechanical Measurements Using Optical Tweezers

Many applications in biosensing, biomaterial engineering and single molecule biophysics require multiple non-covalent linkages between DNA, protein molecules, and surfaces that are specific yet strong. Here, we present a novel method to join proteins and dsDNA molecule at their ends, in an efficient...

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Detalles Bibliográficos
Autores principales: Moayed, Fatemeh, Mashaghi, Alireza, Tans, Sander J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545873/
https://www.ncbi.nlm.nih.gov/pubmed/23336001
http://dx.doi.org/10.1371/journal.pone.0054440