Resolvin D1 attenuates inflammation in lipopolysaccharide-induced acute lung injury through a process involving the PPARγ/NF-κB pathway

BACKGROUND: Docosahexaenoic acid (DHA) and DHA-derived lipid mediators have recently been shown to possess anti-inflammatory and pro-resolving properties. In fact, DHA can down-regulate lipolysaccharide (LPS)-induced activation of NF-κB via a PPARγ-dependent pathway. We sought to investigate the eff...

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Detalles Bibliográficos
Autores principales: Liao, Zenglin, Dong, Jiajia, Wu, Wei, Yang, Ting, Wang, Tao, Guo, Lingli, Chen, Lei, Xu, Dan, Wen, Fuqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545883/
https://www.ncbi.nlm.nih.gov/pubmed/23199346
http://dx.doi.org/10.1186/1465-9921-13-110

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