Cargando…

Enhanced CD8 T-cell anti-viral function and clinical disease in B7-H1-deficient mice requires CD4 T cells during encephalomyelitis

BACKGROUND: Anti-viral CD8 T-cell activity is enhanced and prolonged by CD4 T-cell-mediated help, but negatively regulated by inhibitory B7-H1 interactions. During viral encephalomyelitis, the absence of CD4 T cells decreases CD8 T cell activity and impedes viral control in the central nervous syste...

Descripción completa

Detalles Bibliográficos
Autores principales:	Phares, Timothy W, Stohlman, Stephen A, Hinton, David R, Bergmann, Cornelia C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545890/ https://www.ncbi.nlm.nih.gov/pubmed/23237504 http://dx.doi.org/10.1186/1742-2094-9-269

Ejemplares similares

Distinct CD4 T-cell effects on primary versus recall CD8 T-cell responses during viral encephalomyelitis
por: Hwang, Mihyun, et al.
Publicado: (2015)

Differential Regulation of Self-reactive CD4(+) T Cells in Cervical Lymph Nodes and Central Nervous System during Viral Encephalomyelitis
por: Savarin, Carine, et al.
Publicado: (2016)

Role of CD25(+) CD4(+) T cells in acute and persistent coronavirus infection of the central nervous system
por: de Aquino, Maria Teresa P., et al.
Publicado: (2013)

Dynamics of B cell subsets within the CNS during viral encephalomyelitis
por: Disano, Krista, et al.
Publicado: (2014)

CXCL13 promotes isotype-switched B cell accumulation to the central nervous system during viral encephalomyelitis
por: Phares, Timothy W., et al.
Publicado: (2016)

PKR mediated regulation of inflammation and IL-10 during viral encephalomyelitis
por: Kapil, Parul, et al.
Publicado: (2014)

Sustained TNF production by central nervous system infiltrating macrophages promotes progressive autoimmune encephalomyelitis
por: Valentin-Torres, Alice, et al.
Publicado: (2016)

MMP-independent role of TIMP-1 at the blood brain barrier during viral encephalomyelitis
por: Savarin, Carine, et al.
Publicado: (2013)

Activated GL7(+) B cells are maintained within the inflamed CNS in the absence of follicle formation during viral encephalomyelitis
por: DiSano, Krista D., et al.
Publicado: (2017)

IL-15-independent antiviral function of primary and memory CD8(+) T cells
por: Zuo, Jun, et al.
Publicado: (2005)

IL-21 optimizes T cell and humoral responses in the central nervous system during viral encephalitis
por: Phares, Timothy W., et al.
Publicado: (2013)

IFN-γ protects from lethal IL-17 mediated viral encephalomyelitis independent of neutrophils
por: Savarin, Carine, et al.
Publicado: (2012)

Self-reactive CD4(+) T cells activated during viral-induced demyelination do not prevent clinical recovery
por: Savarin, Carine, et al.
Publicado: (2015)

IL-15 independent maintenance of virus-specific CD8(+) T cells in the CNS during chronic infection
por: Zuo, Jun, et al.
Publicado: (2009)

MMP9 deficiency does not decrease blood–brain barrier disruption, but increases astrocyte MMP3 expression during viral encephalomyelitis
por: Savarin, Carine, et al.
Publicado: (2011)

Intrathecal Humoral Immunity to Encephalitic RNA Viruses
por: Phares, Timothy W., et al.
Publicado: (2013)

Requirement of CD4 Help for Induction of CD8 T Cell Response Specific for Virally Derived H60
por: Ryu, Su Jeong, et al.
Publicado: (2012)

Astrocyte response to IFN-γ limits IL-6-mediated microglia activation and progressive autoimmune encephalomyelitis
por: Savarin, Carine, et al.
Publicado: (2015)

γδT Cells Are Required for CD8(+) T Cell Response to Vaccinia Viral Infection
por: Dai, Rui, et al.
Publicado: (2021)

Linear Fidelity in Quantification of Anti-Viral CD8(+) T Cells
por: Flesch, Inge E. A., et al.
Publicado: (2012)

CD8 is required during positive selection of CD4-/CD8+ T cells
Publicado: (1990)

Aberrant CD3-Positive, CD8-Low, CD7-Negative Lymphocytes May Appear During Viral Infections and Mimic Peripheral T-Cell Lymphoma
por: Klameth, Andreas, et al.
Publicado: (2020)

Change of paradigm: CD8+ T cells as important helper for CD4+ T cells during asthma and autoimmune encephalomyelitis
por: Huber, Magdalena, et al.
Publicado: (2015)

CD4+ T-Cell Help Is Required for Effective CD8+ T Cell-Mediated Resolution of Acute Viral Hepatitis in Mice
por: Trautmann, Tanja, et al.
Publicado: (2014)

Studies on the mechanism of protection from acute viral encephalomyelitis by delayed-type hypersensitivity inducer T cell clones
por: Erlich, Stephanie S., et al.
Publicado: (1989)

Transcriptional signatures of Itk-deficient CD3(+), CD4(+ )and CD8(+ )T-cells
por: Blomberg, K Emelie M, et al.
Publicado: (2009)

Ovalbumin-specific CD4(+) and CD8(+) T cells contribute to different susceptibility for Theiler’s murine encephalomyelitis virus persistence
por: Wannemacher, Rouven, et al.
Publicado: (2023)

Contribution of Herpesvirus Specific CD8 T Cells to Anti-Viral T Cell Response in Humans
por: Sandalova, Elena, et al.
Publicado: (2010)

Direct Presentation Is Sufficient for an Efficient Anti-Viral CD8(+) T Cell Response
por: Xu, Ren-Huan, et al.
Publicado: (2010)

An optimized method for enumerating CNS derived memory B cells during viral-induced inflammation
por: DiSano, Krista D., et al.
Publicado: (2017)

IFN-γ Signaling to Astrocytes Protects from Autoimmune Mediated Neurological Disability
por: Hindinger, Claudia, et al.
Publicado: (2012)

MHC Class I Expression and CD8 T Cell Function: Towards the Cell Biology of T-APC Interactions in the Infected Brain
por: Bergmann, Cornelia, et al.
Publicado: (2008)

Transgenic Interleukin 10 Prevents Induction of Experimental Autoimmune Encephalomyelitis
por: Cua, Daniel J., et al.
Publicado: (1999)

Viral Induced Demyelination
por: Stohlman, Stephen A., et al.
Publicado: (2006)

CD8(+) T cells specific for cryptic apoptosis-associated epitopes exacerbate experimental autoimmune encephalomyelitis
por: Feizi, Neda, et al.
Publicado: (2021)

CD8(+) Resident Memory T Cells and Viral Infection
por: Wu, Xuejie, et al.
Publicado: (2018)

CD8 T Cells Are Required for the Formation of Ectopic Germinal Centers in Rheumatoid Synovitis
por: Kang, Young Mo, et al.
Publicado: (2002)

Interleukin‐10 is a critical regulator of white matter lesion containment following viral induced demyelination
por: Puntambekar, Shweta S., et al.
Publicado: (2015)

Differential effects of anti-CD20 therapy on CD4 and CD8 T cells and implication of CD20-expressing CD8 T cells in MS disease activity
por: Shinoda, Koji, et al.
Publicado: (2023)

CD8 T cell memory in B cell-deficient mice
Publicado: (1996)

Cannot write session to /tmp/vufind_sessions/sess_ounsponmb8osn62papi9cbu04r