Whole genome sequencing of phage resistant Bacillus anthracis mutants reveals an essential role for cell surface anchoring protein CsaB in phage AP50c adsorption

BACKGROUND: Spontaneous Bacillus anthracis mutants resistant to infection by phage AP50c (AP50(R)) exhibit a mucoid colony phenotype and secrete an extracellular matrix. METHODS: Here we utilized a Roche/454-based whole genome sequencing approach to identify mutations that are candidates for conferr...

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Detalles Bibliográficos
Autores principales: Bishop-Lilly, Kimberly A, Plaut, Roger D, Chen, Peter E, Akmal, Arya, Willner, Kristin M, Butani, Amy, Dorsey, Shakia, Mokashi, Vishwesh, Mateczun, Alfred J, Chapman, Carol, George, Matroner, Luu, Truong, Read, Timothy D, Calendar, Richard, Stibitz, Scott, Sozhamannan, Shanmuga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545897/
https://www.ncbi.nlm.nih.gov/pubmed/23098174
http://dx.doi.org/10.1186/1743-422X-9-246

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