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Effects of guaifenesin, N-acetylcysteine, and ambroxol on MUC5AC and mucociliary transport in primary differentiated human tracheal-bronchial cells

BACKGROUND: Therapeutic intervention in the pathophysiology of airway mucus hypersecretion is clinically important. Several types of drugs are available with different possible modes of action. We examined the effects of guaifenesin (GGE), N-acetylcysteine (NAC) and ambroxol (Amb) on differentiated...

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Detalles Bibliográficos
Autores principales: Seagrave, JeanClare, Albrecht, Helmut H, Hill, David B, Rogers, Duncan F, Solomon, Gail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545908/
https://www.ncbi.nlm.nih.gov/pubmed/23113953
http://dx.doi.org/10.1186/1465-9921-13-98