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Cutaneous nociceptors lack sensitisation, but reveal μ-opioid receptor-mediated reduction in excitability to mechanical stimulation in neuropathy

BACKGROUND: Peripheral nerve injuries often trigger a hypersensitivity to tactile stimulation. Behavioural studies demonstrated efficient and side effect-free analgesia mediated by opioid receptors on peripheral sensory neurons. However, mechanistic approaches addressing such opioid properties in pa...

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Detalles Bibliográficos
Autores principales:	Schmidt, Yvonne, Labuz, Dominika, Heppenstall, Paul A, Machelska, Halina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545910/ https://www.ncbi.nlm.nih.gov/pubmed/23116256 http://dx.doi.org/10.1186/1744-8069-8-81

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