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Tropisms of AAV for Subretinal Delivery to the Neonatal Mouse Retina and Its Application for In Vivo Rescue of Developmental Photoreceptor Disorders

BACKGROUND: Adeno-associated virus (AAV) is well established as a vehicle for in vivo gene transfer into the mammalian retina. This virus is promising not only for gene therapy of retinal diseases, but also for in vivo functional analysis of retinal genes. Previous reports have shown that AAV can in...

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Detalles Bibliográficos
Autores principales: Watanabe, Satoshi, Sanuki, Rikako, Ueno, Shinji, Koyasu, Toshiyuki, Hasegawa, Toshiaki, Furukawa, Takahisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545928/
https://www.ncbi.nlm.nih.gov/pubmed/23335994
http://dx.doi.org/10.1371/journal.pone.0054146