Poly(I:C)/Alum Mixed Adjuvant Priming Enhances HBV Subunit Vaccine-Induced Immunity in Mice When Combined with Recombinant Adenoviral-Based HBV Vaccine Boosting

BACKGROUND: Virus-specific cellular immune responses play a critical role in virus clearance during acute or chronic HBV infection. Currently, the commercially available HBV vaccine is combined with alum adjuvant, which stimulates mainly Th2 immune responses. Therefore, development of new therapeuti...

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Detalles Bibliográficos
Autores principales: Chuai, Xia, Chen, Hong, Wang, Wen, Deng, Yao, Wen, Bo, Ruan, Li, Tan, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545998/
https://www.ncbi.nlm.nih.gov/pubmed/23335993
http://dx.doi.org/10.1371/journal.pone.0054126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545998/
https://www.ncbi.nlm.nih.gov/pubmed/23335993
http://dx.doi.org/10.1371/journal.pone.0054126

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