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Determination of the full-genome sequence of hepatitis E virus (HEV) SAAS-FX17 and use as a reference to identify putative HEV genotype 4 virulence determinants

BACKGROUND: Four major genotypes of hepatitis E virus (HEV), the causative agent of hepatitis E, have so far been recognized. While genotypes 3 and 4 are both zoonotic, the disease symptoms caused by the latter tend to be more severe. To examine if specific nucleotide/amino acid variations between g...

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Detalles Bibliográficos
Autores principales: Zhu, Yumin, Yu, Xiaoming, Huang, Fenfen, Yu, Ruisong, Dong, Shijuan, Si, Fusheng, Zhang, Yuanshu, Li, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546022/
https://www.ncbi.nlm.nih.gov/pubmed/23134633
http://dx.doi.org/10.1186/1743-422X-9-264