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Determination of the full-genome sequence of hepatitis E virus (HEV) SAAS-FX17 and use as a reference to identify putative HEV genotype 4 virulence determinants
BACKGROUND: Four major genotypes of hepatitis E virus (HEV), the causative agent of hepatitis E, have so far been recognized. While genotypes 3 and 4 are both zoonotic, the disease symptoms caused by the latter tend to be more severe. To examine if specific nucleotide/amino acid variations between g...
Autores principales: | Zhu, Yumin, Yu, Xiaoming, Huang, Fenfen, Yu, Ruisong, Dong, Shijuan, Si, Fusheng, Zhang, Yuanshu, Li, Zhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546022/ https://www.ncbi.nlm.nih.gov/pubmed/23134633 http://dx.doi.org/10.1186/1743-422X-9-264 |
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