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Carbon nanoparticles induce ceramide- and lipid raft-dependent signalling in lung epithelial cells: a target for a preventive strategy against environmentally-induced lung inflammation
BACKGROUND: Particulate air pollution in lung epithelial cells induces pathogenic endpoints like proliferation, apoptosis, and pro-inflammatory reactions. The activation of the epidermal growth factor receptor (EGFR) is a key event responsible for signalling events involving mitogen activated protei...
Autores principales: | Peuschel, Henrike, Sydlik, Ulrich, Grether-Beck, Susanne, Felsner, Ingo, Stöckmann, Daniel, Jakob, Sascha, Kroker, Matthias, Haendeler, Judith, Gotić, Marijan, Bieschke, Christiane, Krutmann, Jean, Unfried, Klaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546038/ https://www.ncbi.nlm.nih.gov/pubmed/23228165 http://dx.doi.org/10.1186/1743-8977-9-48 |
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