Cargando…
In vivo evaluation of antimyotonic efficacy of β-adrenergic drugs in a rat model of myotonia
The sodium channel blocker mexiletine is considered the first-line drug in myotonic syndromes, a group of muscle disorders characterized by membrane over-excitability. We previously showed that the β-adrenoceptor modulators, clenbuterol and propranolol, block voltage-gated sodium channels in a manne...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Pergamon Press
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546166/ https://www.ncbi.nlm.nih.gov/pubmed/23000075 http://dx.doi.org/10.1016/j.neuropharm.2012.09.006 |