Cocaine Induced Vasculitis: Have We Found a Culprit?

Cocaine abuse is relatively common in our society. To enhance profitability and acceptability of the product, it is not uncommon for illicit drugs to undergo several processes. The Drug Enforcement Agency (DEA) has reported that seventy percent (70%) of cocaine seized at USA borders has been adulter...

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Autores principales: Sánchez-Cruz, Alfredo, Marrero, Sylmarie, Betancourt, José, Andino, Myrna, Lopez, Adolfo, Gutierrez-Nuñez, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546447/
https://www.ncbi.nlm.nih.gov/pubmed/23346447
http://dx.doi.org/10.1155/2012/982361
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author Sánchez-Cruz, Alfredo
Marrero, Sylmarie
Betancourt, José
Andino, Myrna
Lopez, Adolfo
Gutierrez-Nuñez, Jose
author_facet Sánchez-Cruz, Alfredo
Marrero, Sylmarie
Betancourt, José
Andino, Myrna
Lopez, Adolfo
Gutierrez-Nuñez, Jose
author_sort Sánchez-Cruz, Alfredo
collection PubMed
description Cocaine abuse is relatively common in our society. To enhance profitability and acceptability of the product, it is not uncommon for illicit drugs to undergo several processes. The Drug Enforcement Agency (DEA) has reported that seventy percent (70%) of cocaine seized at USA borders has been adulterated with levamisole, previously used as chemotherapeutic and immunomodulator for several conditions. Among the side effects of levamisole-adulterated cocaine, necrotizing vasculitis is the more dramatic. We report three cases of necrotizing vasculitis associated with antineutrophils cytoplasmic antibodies (ANCAs) positivity, linked to the use of cocaine. To our knowledge, these are the first cases of cocaine induced vasculitis reported in the Caribbean.
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spelling pubmed-35464472013-01-23 Cocaine Induced Vasculitis: Have We Found a Culprit? Sánchez-Cruz, Alfredo Marrero, Sylmarie Betancourt, José Andino, Myrna Lopez, Adolfo Gutierrez-Nuñez, Jose Case Rep Rheumatol Case Report Cocaine abuse is relatively common in our society. To enhance profitability and acceptability of the product, it is not uncommon for illicit drugs to undergo several processes. The Drug Enforcement Agency (DEA) has reported that seventy percent (70%) of cocaine seized at USA borders has been adulterated with levamisole, previously used as chemotherapeutic and immunomodulator for several conditions. Among the side effects of levamisole-adulterated cocaine, necrotizing vasculitis is the more dramatic. We report three cases of necrotizing vasculitis associated with antineutrophils cytoplasmic antibodies (ANCAs) positivity, linked to the use of cocaine. To our knowledge, these are the first cases of cocaine induced vasculitis reported in the Caribbean. Hindawi Publishing Corporation 2012 2012-12-30 /pmc/articles/PMC3546447/ /pubmed/23346447 http://dx.doi.org/10.1155/2012/982361 Text en Copyright © 2012 Alfredo Sánchez-Cruz et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Sánchez-Cruz, Alfredo
Marrero, Sylmarie
Betancourt, José
Andino, Myrna
Lopez, Adolfo
Gutierrez-Nuñez, Jose
Cocaine Induced Vasculitis: Have We Found a Culprit?
title Cocaine Induced Vasculitis: Have We Found a Culprit?
title_full Cocaine Induced Vasculitis: Have We Found a Culprit?
title_fullStr Cocaine Induced Vasculitis: Have We Found a Culprit?
title_full_unstemmed Cocaine Induced Vasculitis: Have We Found a Culprit?
title_short Cocaine Induced Vasculitis: Have We Found a Culprit?
title_sort cocaine induced vasculitis: have we found a culprit?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546447/
https://www.ncbi.nlm.nih.gov/pubmed/23346447
http://dx.doi.org/10.1155/2012/982361
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