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Using an experimental medicine model to understand the antidepressant potential of the N-Methyl-D-aspartic acid (NMDA) receptor antagonist memantine
There is growing interest in the role of the glutamatergic system both in depression and as a novel target for treatments. Preclinical studies suggested that the non-competitive N-Methyl-D-aspartic acid (NMDA) receptor antagonist memantine might have antidepressant properties, but a randomised contr...
Autores principales: | Pringle, A, Parsons, E, Cowen, LG, McTavish, SF, Cowen, PJ, Harmer, CJ |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546643/ https://www.ncbi.nlm.nih.gov/pubmed/22596208 http://dx.doi.org/10.1177/0269881112446535 |
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